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Appl. Environ. Microbiol. doi:10.1128/AEM.00225-08
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Genetic Diversity of Porphyromonas gingivalis Recovered from Single "Refractory" Periodontitis Sites

Institute of Oral Biology, University of Oslo, 0316 Oslo, Norway; Department of Bacteriology and Immunology, Norwegian Institute of Public Health, 0403 Oslo, Norway

^* To whom correspondence should be addressed. Email: morteene{at}odont.uio.no.

	Abstract

Multilocus sequence typing (MLST) and fimA genotyping was performed on Porphyromonas gingivalis isolates from 15 subjects with "refractory" periodontitis. Several sequence types (STs) were detected in most individual pockets. The variation indicated recombination at the recA and pepO genes. The prevalence of fimA genotypes II and IV confirmed their association to periodontitis.